Medical Waste Regulations in Ohio (2026)

Generator registration, storage limits, approved treatment, transport rules, and penalties under Ohio Environmental Protection Agency, Division of Materials and Waste Management, with the primary statute behind every line.

Last verified against primary sources.
Changelog
  • Initial publication. Confirmed against ORC Chapter 3734, ORC 3734.99, and OAC Chapter 3745-570 (rules 3745-570-31, -120, -125, -130, -201) on codes.ohio.gov, and the Ohio EPA Infectious Waste program page.

Ohio medical waste rules at a glance

Regulated medical waste rules in Ohio, at a glance
Governing agencyOhio Environmental Protection Agency, Division of Materials and Waste Management
Primary statute / rule
  • ORC Chapter 3734: Solid and Hazardous Wastes (enabling statute; defines infectious waste)
  • OAC Chapter 3745-570: Infectious Waste Rules (operative rules, effective April 6, 2025; replaced OAC Chapter 3745-27)
Generator registrationAny person who generates fifty pounds or more of infectious waste in any one month at any one location is a large generator and must submit an application for a registration certificate to Ohio EPA not later than thirty days after the last day of the month in which that threshold was reached, with a nonrefundable application fee of one hundred forty dollars. The certificate is valid for three years unless revoked. [source]
On-site storage time limitOhio sets no fixed day limit on how long a generator may store its own infectious waste, but requires that the waste be kept in a nonputrescent state using refrigeration or freezing when necessary; any waste that becomes putrescent must be immediately refrigerated or frozen and treated as soon as possible. Treatment facilities may store untreated infectious waste for no more than fourteen days, and after treatment a generator must ensure the treated waste reaches a treatment or disposal facility not later than sixty days after the container is closed. [source]
Approved treatment methods
  • Incineration (OAC 3745-570-202)
  • Autoclaving / steam sterilization (OAC 3745-570-203)
  • Chemical treatment with a sodium hypochlorite solution for cultures (OAC 3745-570-204)
  • Ozone exposure treatment (OAC 3745-570-205)
  • Director-approved alternative treatment technologies (OAC 3745-570-210 and 3745-570-211)
[source]
Transport / manifest rulesOhio uses a single disposal paper rather than a multi-copy, hazardous-waste-style manifest. Treated infectious waste transported off the premises where it was generated must be accompanied by a disposal paper that identifies the treatment facility and carries a signed, dated certification that the waste was treated in accordance with the chapter, and that paper travels with the waste to the solid waste disposal facility. Generators must keep copies of all disposal papers for at least five years. [source]
On-site treatment allowed?Yes. A generator may treat its own infectious waste at a treatment facility it owns or operates using any approved method in OAC 3745-570-201, and many generator-operated treatment units are exempt from the separate permit-to-install requirement. Treated waste leaving the premises must still be accompanied by a disposal paper. [source]
Penalty rangeEnforced under ORC 3734.99. Whoever recklessly violates Chapter 3734 (which includes the infectious waste provisions) is guilty of a felony and shall be fined at least $10,000 but not more than $25,000, or imprisoned, or both; on a second or subsequent conviction the fine is at least $20,000 but not more than $50,000 per day of violation, with each day a separate offense. Administrative and civil enforcement is also available under ORC 3734.13. [source]

What is unique about Ohio

Ohio reorganized its entire infectious waste rule set in 2025. The requirements that for decades lived in OAC Chapter 3745-27 moved into a new, dedicated OAC Chapter 3745-570 effective April 6, 2025, so legacy citations to 3745-27-30 through 3745-27-36 are no longer the operative rules. Ohio also splits authority: Ohio EPA registers generators and regulates treatment, while local boards of health license most infectious waste treatment facilities under ORC 3734. The 50-pound-per-month threshold is the dividing line between small generators, which can largely dispose of treated waste as solid waste, and large generators, which must register and pay the $140 fee.

Frequently asked questions

Who regulates infectious (medical) waste in Ohio?

The Ohio Environmental Protection Agency, Division of Materials and Waste Management, regulates infectious waste under ORC Chapter 3734 and the rules in OAC Chapter 3745-570. Local boards of health license most infectious waste treatment facilities.

Do I have to register as an infectious waste generator in Ohio?

You must register with Ohio EPA if you generate fifty pounds or more of infectious waste in any one month at one location. The application is due within thirty days after the end of that month, costs a nonrefundable $140, and the resulting registration certificate is valid for three years (OAC 3745-570-125).

How long can infectious waste be stored before treatment in Ohio?

Ohio sets no fixed day limit on a generator storing its own waste, but the waste must be kept nonputrescent using refrigeration or freezing when necessary, and anything that becomes putrescent must be refrigerated or frozen and treated immediately. Treatment facilities may hold untreated waste for no more than fourteen days, and treated waste must reach disposal within sixty days of the container being closed (OAC 3745-570-31).

What treatment methods are approved for infectious waste in Ohio?

Incineration, autoclaving, chemical treatment with a sodium hypochlorite solution for cultures, and ozone exposure are the approved methods, plus any alternative technology approved by the Ohio EPA director (OAC 3745-570-201).